Pediatric Headache in Korea: Beyond a Common Complaint to a Chronic Neurological Condition

Article information

Headache Pain Res. 2026;.hpr.2026.0006
Publication date (electronic) : 2026 February 13
doi : https://doi.org/10.62087/hpr.2026.0006
1Department of Pediatrics, Pusan National University Children’s Hospital, Pusan National University School of Medicine, Yangsan, Republic of Korea
2Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Republic of Korea
Correspondence: Yun Jin Lee, M.D., Ph.D. Department of Pediatrics, Pusan National University Children’s Hospital, 20 Geumo-ro, Mulgeum-eup, Yangsan 50612, Republic of Korea Tel: +82-55-360-2180, Fax: +82-55-360-2181, E-mail: jinnyeye@naver.com
Received 2026 January 30; Accepted 2026 January 31.

INTRODUCTION

Pediatric headache is frequently dismissed as a minor ailment rather than recognized as a chronic condition capable of causing substantial disability. However, the lived experiences of affected children—often characterized by chronic absenteeism, cognitive impairment, and strained family dynamics—present a markedly different reality. Three recent reviews in Headache and Pain Research help explain why this clinical gap persists: the challenges of diagnostic framing,1 the neurological risks associated with undertreated attacks,2 and the persistent “interictal” burden that affects patients even between episodes.3 When these issues are examined in the context of Korean epidemiological data and healthcare realities, a consistent pattern emerges: pediatric headache in Korea is both widespread and disabling, yet structurally positioned for under-treatment.

THE REALITY: PREVALENCE IN THE KOREAN CONTEXT

Globally, pediatric headache represents a major public health concern, with prevalence increasing steadily as children progress into adolescence.4 More recent syntheses commonly estimate migraine prevalence at approximately 11% among children and adolescents, and rates rise further during adolescence.5 Korean data mirror these international trends with striking consistency. A nationwide survey of Korean schoolchildren reported a 1-year headache prevalence of 29.1%, with higher rates observed in girls and in urban or suburban settings.6 At this level of frequency, multiple students in a typical classroom are likely to be living with recurrent headache. In addition, Kwon1 reports that chronic primary headache affects 1%–2% of adolescents, while nearly one quarter experience broader functional somatic symptoms. Collectively, these findings place pediatricians at a complex intersection of neurology and stress-related biological processes.

THE BURDEN OR HIDDEN TOLL: LIFE BETWEEN ATTACKS

Even in the absence of active pain, migraine-related burden frequently persists. Kim and Schwedt3 emphasize the concept of “interictal burden,” defined as a constellation of fatigue, cognitive dysfunction (“brain fog”), sensory hypersensitivity, anticipatory anxiety, and social withdrawal that continues between acute attacks. This hidden burden is particularly consequential in Korea, where academic performance is closely tied to consistent daily attendance and sustained cognitive demand. Interictal symptoms—including impaired concentration, planning difficulties, and anxiety about future attacks—often result in school presenteeism (attending school while cognitively impaired) and reduced participation in after-school activities, accompanied by social withdrawal. Moreover, stigma surrounding invisible pain frequently compels children to conceal symptoms, delaying timely medical evaluation and intervention.3

THE TREATMENT GAP: DANGERS OF “MEDICATION UNDERUSE”

A common misconception is that medication overuse is the primary driver of headache worsening. Moon and Chung,2 however, argue that medication underuse—manifesting as delayed or inadequate treatment—is equally hazardous because it plays a critical role in perpetuating neuroinflammation and central sensitization, thereby increasing attack frequency and treatment resistance. Families who are primarily cautioned about the risks of frequent analgesic use may delay intervention until attacks become severe, which reduces the effectiveness of acute therapy and increases the risk of chronification.2

In Korea, specific structural hurdles exacerbate this problem:

● Low utilization of migraine-specific acute therapy (triptans): A large population-based Korean analysis found that migraine-specific triptans are prescribed to only approximately 10% of migraine patients, despite established efficacy.7 Although these data are not pediatric-specific, they reflect a broader national pattern of underutilization that likely influences pediatric practice.

● Limited approved pediatric triptan options: While multiple triptans are available internationally, only almotriptan is approved for use in Korean adolescents, narrowing clinician choice and encouraging reliance on non-specific analgesics.8

● Reliance on non-specific analgesics and early discontinuation: Newly diagnosed migraine patients are often treated primarily with nonsteroidal anti-inflammatory drugs or acetaminophen rather than migraine-specific agents, an approach that may fail to interrupt pathways leading to chronification.2,9

WHY DIAGNOSTIC FRAMING MATTERS: “SOMATIC” DOES NOT MEAN BENIGN

Kwon’s review1 addresses a critical diagnostic “gray zone”: pediatric headache may meet the International Classification of Headache Disorders, third edition criteria for a primary headache disorder, may reflect somatic symptom and related disorders, or may involve overlapping features of both. In clinical practice, labeling headache as “stress-related” or “functional” can inadvertently result in therapeutic withdrawal, characterized by repeated diagnostic testing, reassurance without structured follow-up, and limited active management. Kwon1 advocates a holistic approach that integrates psychoeducation with non-pharmacological interventions, such as cognitive behavioral therapy (CBT) and biofeedback, to support functional improvement across both primary headache and somatic presentations. Despite this recommendation, access to CBT, biofeedback, school-based accommodations, and interdisciplinary headache care remains inconsistent across Korea.

A STRATEGIC PATH FORWARD FOR KOREA

To improve outcomes, clinical priorities must shift from simply counting headache days to actively preventing disability:

● Prioritize early intervention (avoid underuse): Families require clear, explicit guidance regarding when to initiate treatment to reduce the risks associated with medication underuse.2

● Broaden assessment: Treatment success should be evaluated using functional outcomes, including school participation and interictal burden, rather than pain frequency alone.3

● Unified framework: Moving beyond the “organic versus psychogenic” dichotomy allows clinicians to focus on shared neurological mechanisms, such as central sensitization.1

● Korea-specific policy expansion: There is an urgent need to expand approved pediatric pharmacologic options and strengthen school-based support systems.8

CONCLUSION

Pediatric headache is common, disabling, and insufficiently treated largely because its clinical significance is underestimated. Recognizing headache as a chronic biopsychosocial disorder with both ictal and interictal consequences necessitates a fundamental shift in clinical priorities. Early, proactive, and integrated management—combining timely pharmacologic treatment, psychological support, and family-centered education—is essential to prevent long-term disability. Failure to act risks exposing children to prolonged and avoidable suffering, impaired development, and entrenched pain pathways. Pediatric headache represents a serious neurological challenge, and addressing this condition appropriately requires the healthcare system to deliver the same level of sustained therapeutic commitment typically reserved for other major chronic pediatric disorders.

Notes

AVAILABILITY OF DATA AND MATERIAL

Not applicable.

AUTHOR CONTRIBUTIONS

Conceptualization: YJL; Writing–original draft: YJL; Writing–review & editing: YJL.

CONFLICT OF INTEREST

Yun Jin Lee is the Associate Editor of Headache and Pain Research and was not involved in the review process of this article. The author has no other conflicts of interest to declare.

FUNDING STATEMENT

Not applicable.

ACKNOWLEDGMENTS

Not applicable.

References

1. Kwon HE. Headache as a somatic symptom in pediatrics: diagnosis and integrated management. Headache Pain Res 2025;26:193–199. 10.62087/hpr.2025.0016.
2. Moon HS, Chung PW. The hidden risks of medication underuse in migraine progression. Headache Pain Res 2025;26:209–217. 10.62087/hpr.2025.0019.
3. Kim SK, Schwedt TJ. Interictal burden of migraine: a narrative review. Headache Pain Res 2025;26:200–208. 10.62087/hpr.2025.0018.
4. Abu-Arafeh I, Razak S, Sivaraman B, Graham C. Prevalence of headache and migraine in children and adolescents: a systematic review of population-based studies. Dev Med Child Neurol 2010;52:1088–1097. 10.1111/j.1469-8749.2010.03793.x. 20875042.
5. Ishiyama S, Matsumura A, Hayakawa M, Kohno Y, Ishikawa E. Headache prevalence and impact among school-aged children in a Japanese town: the AMI-GRAINES study. Sci Rep 2026;16:1144. 10.1038/s41598-025-30859-9. 41339437.
6. Rho YI, Chung HJ, Lee KH, et al. Prevalence and clinical characteristics of primary headaches among school children in South Korea: a nationwide survey. Headache 2012;52:592–599. 10.1111/j.1526-4610.2011.02001.x. 21929660.
7. Ha WS, Jeong J, Song S, Yum J, Chu MK. Trends in triptan usage in Korea: a population-based cohort study. J Korean Med Sci 2024;39:e222. 10.3346/jkms.2024.39.e222. 39137809.
8. Kim S. Pediatric headache: a narrative review. J Yeungnam Med Sci 2022;39:278–284. 10.12701/jyms.2022.00528. 36102115.
9. Rhew K. Medication prescribing status in pediatric patients with migraine. Korean J Clin Pharm 2022;32:178–184. 10.24304/kjcp.2022.32.3.178.

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