- Update on Tension-type Headache
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Hye Jeong Lee, Soo-Jin Cho, Jong-Geun Seo, Henrik Winther Schytz
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Headache Pain Res. 2025;26(1):38-47. Published online December 30, 2024
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DOI: https://doi.org/10.62087/hpr.2024.0025
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- Tension-type headache (TTH) is the most common type of headache, characterized by mild to moderate intensity, bilateral, with a pressing or tightening (non-pulsating) quality. Migraine and TTH can occur in the same person, and their risk factors and treatments can overlap. However, TTH receives less attention than migraine. Furthermore, despite the expanding market for migraine treatments targeting calcitonin gene-related peptide (CGRP) mechanisms, the lack of evidence regarding mechanisms related to CGRP-related mechanisms in TTH continues to be neglected. There remains a need to develop effective preventive treatments for chronic TTH, which imposes a very high burden of disease. From this perspective, this review aims to provide the latest evidence on TTH.
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Citations
Citations to this article as recorded by  - Tension-Type Headache and Primary Stabbing Headache: Primary Headaches Beyond Migraine
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The Journal of Headache and Pain.2025;[Epub] CrossRef - Trends in the Burden of Headache Disorders in Europe, 1990–2021: A Systematic Analysis from the Global Burden of Disease Study 2021
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